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The decelerating age adjusted LTL attrition
2018-11-13
The decelerating age-adjusted LTL attrition in cancer cases as they approach diagnosis suggests that telomere ICG001 mechanisms may be activated in the blood due to cancer initiation. Telomere integrity is primarily maintained by telomerase, which catalyzes the synthesis of telomere repeats and adds
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br Authorship contributions br Disclosure of conflicts of in
2018-11-13
Authorship contributions Disclosure of conflicts of interest Acknowledgements Introduction Melanomas are among the most commonly occurring cancers. Crude incidence rates in Australia (AIHW, 2014) and the USA (SEER, 2014) were approximately 50 cases (in 2010) and 20 cases (in 2011) per 10
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We chose to study mAb
2018-11-13
We chose to study mAb41 because it is a potent neutralizing antibody that arises from an antigenic region that can induce both neutralizing and non-neutralizing antibodies, providing a basis for investigating whether mAb41 mimotopes could induce immune responses with mAb41-like properties, including
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So how good is TILDA in measuring
2018-11-13
So how good is TILDA in measuring HIV that is capable of replicating? The frequency of CD4+ T histamine-2 receptor antagonist with inducible RNA by TILDA is within the realm of expectation. First, early treated individuals harbor fewer such cells than chronically treated individuals. Second, the siz
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br Introduction Despite documented complexities with epidemi
2018-11-13
Introduction Despite documented complexities with epidemiological definitions and clinical diagnosis (Scott et al., 2012), the global burden of pneumonia, including healthcare-associated and ventilator-associated pneumonia, clearly remains significant. Estimates from the Global Burden of Disease
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Tedizolid HCl Nematode species display remarkable versatilit
2018-11-13
Nematode species display remarkable versatility in relation to the diverse trophic niches that they occupy and display substantial diversity at morphological levels of the intestine (Munn and Greenwood, 1984). Hence, while many basic intestinal cell characteristics are likely to be broadly conserved
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br Materials and Methods br Results br Discussion
2018-11-13
Materials and Methods Results 4. Discussion Significant BOLD signals when viewing affectively positive stimuli were identified in a specific pontine region. It is the affective content but not other perceptual properties (verified by the masked images condition) that explains this significa
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Anemia is common in diabetes
2018-11-13
Anemia is common in diabetes, with multiple causes (Thomas et al., 2003, 2006; Craig et al., 2005). Low RBC ascorbate might contribute to anemia, possibly via low grade chronic hemolysis produced by RBC rigidity. Future studies of diabetic subjects will include measurement of cell-free hemoglobin an
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Although there was no difference in the mean age of
2018-11-12
Although there was no difference in the mean age of onset between acral and mucosal melanomas, KIT mutation in mucosal melanomas occurred more than a decade earlier than that in acral melanomas. Regarding the sex factor, we noticed that KIT mutation among our few cases is more commonly seen in male
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Introduction The skin is the
2018-11-12
Introduction The skin is the largest organ in mammals. It covers the surface of the body and consists of three main layers: the surface epidermis, the subjacent dermis, and the subcutaneous tissue (the lowest layer). An important function of the skin is to protect an animal\'s body from external st
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br Introduction Solar ultraviolet radiation UVR
2018-11-12
Introduction Solar ultraviolet GSK461364 (UVR) is the most common environmental cause of the vast majority of skin disorders including skin cancer. Epidemiological studies have disclosed a strong association between solar UVR and all major types of skin cancer. Although many factors such as advan
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br Discussion BPDCN is an
2018-11-12
Discussion BPDCN is an aggressive, rare hematologic neoplasm that mainly affects elderly individuals 60 to 70 years of age, with a male predominance and a median survival of 12–16 months. Most patients present with multiple nonpruritic cutaneous lesions followed by involvement of the lymph nodes,
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Extensive work on the influence of pin geometry
2018-11-12
Extensive work on the influence of pin geometry on mechanical properties of 2014 aluminium alloy friction stir welds has been carried out by Zhao et al. [18]. Taper screw thread pin weld was reported to have the highest weld joint efficiency (75%) compared to the threaded cylindrical tool pin profil
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When the virial coefficients of propellant gas at
2018-11-12
When the virial coefficients of propellant gas at high temperature and pressure are calculated, the second virial coefficients of CO, H2 and N2 can be obtained by Eqs. (4) ~ (6); the second virial coefficients of H2O and CO2 can be obtained by Eq. (7)[17] and Eq. (8)[18]; the third virial coefficien
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Introductory Thermobaric weapons are classified as a subcomp
2018-11-12
Introductory Thermobaric weapons are classified as a subcomponent of a larger family of weapon systems which are commonly known as volumetric weapons. The volumetric weapons include thermobaric and fuel-air explosives (FAE, aerosol bombs in German). The term “thermobaric” is a compound word derived