• To enhance the accuracy of SEs in eliminating

  2024-08-15

  

  To enhance the accuracy of SEs in eliminating cancer cells, the mAb recognized by specific Phosphatase Inhibitor Cocktail 1 (100X in DMSO) on tumor cells were fused with SEs. Fab C215 or C242 fused with SEA promoted apoptosis in human colon carcinoma cells via Fas (Dohlsten et al., 1994, Litton et

• An in vitro assay in which endothelial cells form

  2024-08-15

  

  An in vitro assay in which endothelial cells form 3D tube-like structures was used to investigate effects of dNK on vessel stability. The results indicate that dNK cells from women with high spiral artery resistance index had reduced ability to activate endothelial cells, since endothelial cells pre

• It has been well established that shortly after systemic

  2024-08-15

  

  It has been well established that shortly after systemic inflammation, NADPH oxidase and iNOS activity were increased in the Nuclear/Cytosol Fractionation Kit and lead to overproduction of reactive oxygen species (ROS) and NO [66]. Moreover, previous studies indicated that Ang II induced an increas

• In summary the CV and

  2024-08-15

  

  In summary, the CV and renal benefits of sacubitril/valsartan in HF patients are attributed to the increased levels of peptides that are degraded by neprilysin and the simultaneous inhibition of the effects of AT1 receptor by valsartan (Fig. 1). Physical and chemical properties Sacubitril/Valsar

• Prostate cell growth and prostate carcinogenesis are

  2024-08-15

  

  Prostate cell growth and prostate carcinogenesis are not only mediated by androgens, they are also dependent on functional insulin receptor (IR) and insulin-like growth factor-1 (IGF-1) receptor (IGF1R) signaling. Previous studies addressed this issue and reported a correlation between high insulin

• The zinc transporter proteins are members of

  2024-08-15

  

  The zinc transporter proteins are members of the SLC superfamily of metal transporters, and comprise two structurally and functionally different groups, the zinc-importer (ZIP; Zrt-, Irt-like proteins) family (SLC39A), which regulate zinc transport into the cytoplasm from outside the cell and from i

• AAT enzyme activity was readily detected in

  2024-08-15

  

  AAT enzyme activity was readily detected in crude cell-free extracts obtained from berry tissues of all accessions but displayed different substrate selectivities (Fig. 2). Cell-free extracts derived from ‘Muscat Hamburg’ berries showed the highest AAT activity with all alcoholic substrates tested,

• br Disclosure br Acknowledgments br Introduction Deeper unde

  2024-08-15

  

  Disclosure Acknowledgments Introduction Deeper understanding of the pathobiology of non-small cell lung cancer (NSCLC) has led to the development of small Paeonol synthesis that target genetic mutations known to play critical roles in the progression to metastatic disease. Mutations in epi

• Various compounds have been designed

  2024-08-15

  

  Various compounds have been designed to inhibit aldose reductase (AR) [12]. These compounds can be classified into two main categories, the first category comprises those containing a carboxylic PD 0332991 receptor moiety, for example, 3-thiazolidineacetic acid derivative, which has been reported t

• Though we have proved that VA could suppress hepatic

  2024-08-14

  

  Though, we have proved that VA could suppress hepatic gluconeogenesis, the mechanisms of VA on gluconeogenesis in vivo and in vitro remain unclear. AMP-activated protein kinase (AMPK), which is called an energy receptor enzyme, is widely expressed in liver and other tissues [23]. AMPK has become ano

• br Experimental procedures br Results br Discussion Major de

  2024-08-14

  

  Experimental procedures Results Discussion Major depressive disorder is among the leading causes of disability worldwide (Vos et al., 2015). One of the major causal or exacerbating factors of depression is long term stress or psychological trauma (Liu and Alloy, 2010). Dysregulation of the

• br Application of bamboo in the

  2024-08-14

  

  Application of bamboo in the food and pharmaceutical industry For decades, the application of antioxidants in the food and pharmaceutical industry has been widespread. In the past, antioxidants were previously used to control oxidation and retard spoilage but today, many are used because of putat

• br Methodology br Antibiotics in lakes

  2024-08-14

  

  Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on 12-O-tetradecanoyl phorbol-13-acetate and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics rep

• Optical coherence tomography angiography is another promisin

  2024-08-14

  

  Optical coherence tomography angiography is another promising method for the assessment of corneal neovascularization. This relatively new modality is not yet widely used in part because of current limitations in the definition of images produced, lack of functional information, and inability to det

• This suggestion was confirmed by immunohistochemical

  2024-08-13

  

  This suggestion was confirmed by immunohistochemical studies in which the immunoreactivity of the enzyme was actually higher at the earlier rather than at the advanced stages of the disease. Importantly, a later study showed that the biochemical signature of 12/15LO enzymatic activation (i.e., 12-HE

16335 records 104/1089 page Previous Next First page 上5页 101102103104105 下5页 Last page