• To learn what specific genes and biological pathways are

  2018-10-24

  

  To learn what specific genes and biological pathways are involved in the response to pro-oxidant exposure, we performed RNA-seq analysis on 72-hpf embryos after 48 hr of pro-oxidant exposure; the heatmap analysis of unsupervised clustering is shown in Figure 3D. We found 316 genes upregulated (incre

• Constituting about of all cells in the

  2018-10-24

  

  Constituting about 40% of all cells in the brain, astrocytes have long been classified as mere passive supporting cells that, for example, promote survival and functional synaptic formation of neurons; however, astrocytes are also essential for the phagocytic elimination of synapses, which refines n

• Second donor type iPS DCregs activated donor

  2018-10-24

  

  Second, donor-type iPS-DCregs activated donor-specific Tregs. Donor-type DCregs expressing donor MHC molecules traveled to the recipient\'s secondary lymphoid tissues and interacted with T cells through the “direct pathway” of allorecognition. The direct pathway of allorecognition is considered to b

• br Conclusion The Hartree Fock approach was used for

  2018-10-24

  

  Conclusion The Hartree–Fock approach was used for finding wave functions and single-electron energies of the sodium liver x receptor in the ground and the excited states. The photoionization amplitudes and the photoabsorption cross-sections for this atom were computed through RPAE which explains

• was introduced for convenience of analysis where are the

  2018-10-24

  

  was introduced for convenience of analysis, where are the layer thickness values in dimensional units Two groups of phonon modes (I and II) can be identified in the obtained solutions. These modes have the following frequencies: The first type of solutions deals with the phonons of A(LO) and E(

• As a comparison Fig d

  2018-10-24

  

  As a comparison, Fig. 2d shows the shape of the curve for the probe approaching the measured sample (curve 2) for the case when the standard system for detecting the position of the probe tip is used. This system is based on the principle of registering the position of the laser beam reflected from

• ret proto oncogene br Convergence study and computational re

  2018-10-24

  

  Convergence study and computational results To adequately choose the size of the finite elements and the integration step, we examined the convergence of the results as a function of these parameters. Given the physical nature of the simulated vibration process, the grid dimension and the integra

• Embelin Although no other previous study has investigated

  2018-10-24

  

  Although no other previous study has investigated the associations of social support from both life domains and six different sources each and in relation to diverse health and work-related outcomes, parts of the study findings have been reported previously in earlier studies. Thus Sinokki and colle

• br Healthcare pathway evaluations In our example we will mak

  2018-10-24

  

  Healthcare pathway evaluations In our example, we will make these evaluations as assessments against hypothetical “ideal” behaviours. Our illustrative definition of “ideal” behaviour involves access to regulated healthcare providers and minimal delays to care where the illness requires the patien

• Afanasieff et al obtained results that show a relatively

  2018-10-23

  

  Afanasieff et al. (2002) obtained results that show a relatively more important role of the macroeconomic determinants of bank spread, although in the authors’ conclusion it was mentioned that these factors may have reached their “limit” of influence, being necessary to make alterations in the micro

• In this paper we assess the extent to which the

  2018-10-23

  

  In this paper we assess the extent to which the imposition of a no-arbitrage restriction on the DNS setting brings additional forecasting gains by providing an empirical evidence based on a large data set of constant-maturity future contracts of the Brazilian Inter Bank Deposit Contract (DI1) which

• According to several studies hotspots of RAS mutations have

  2018-10-23

  

  According to several studies, hotspots of RAS mutations have been identified in codons 12, 13, 59, 61, 117, and 146, which are considered to induce conformational changes into constitutively active forms (Prior et al., 2012; Smith et al., 2010). In addition, these gene mutations tend to occur in a m

• br Author Contributions br Acknowledgments This

  2018-10-23

  

  Author Contributions Acknowledgments This work was supported in part by the Canadian Institutes of Health Research (a grant to Q.B.L, #105218, and a New Investigator Award to Q.B.L), the Ontario Ministry of Research and Innovation (an Early Researcher Award to Q.B.L, #112621), and Natural Scie

• br Methods br Results br Discussion A main health

  2018-10-23

  

  Methods Results Discussion A main health obstacle to control TB is that latent bacilli may remain viable for decades and reactivate later to cause active TB. Thus, there is a need to identify LTBI individuals and treat them to eliminate the risk of developing TB. Since there is no diagnosti

• Finally we hypothesized that hepcidin concentrations might i

  2018-10-23

  

  Finally we hypothesized that hepcidin concentrations might influence the subsequent risk of malaria. Intriguing data from mouse studies suggest that hepcidin might play a role in modulating clinical malaria (Wang et al., 2011; Portugal et al., 2011), but we are not aware of any previous studies that

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