• br Conclusions br Study limitations br Conflict of

  2019-04-15

  

  Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum c

• Our results are consistent with previous findings in other m

  2019-04-15

  

  Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23]

• Baseline WBC count and baseline measures

  2019-04-15

  

  Baseline WBC count and baseline measures of hepatic and renal function for responders and nonresponders are shown in Table 1. No relationship was evident between responders to decitabine or treatment choice and baseline WBC counts, or between responders and baseline measures of hepatic function (ALT

• br Discussion Sato et al first reported

  2019-04-15

  

  Discussion Sato et al. [11] first reported TCM in 1990, and thereafter, numerous cases were reported in the late 2000s. In 85% of the cases, TCM onset was preceded by an emotional or physical stress event, however, in 15% of the cases, the presence of a stress trigger could not be detected [2]. M

• There has been scant prior research focusing on

  2019-04-15

  

  There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath

• We have recently completed a

  2019-04-11

  

  We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co

• A recent meta analysis has shown that an

  2019-04-11

  

  A recent meta-analysis has shown that an enlarged LA increases the risk of AF recurrence after a single CPVI, regardless of the follow-up duration [5]. This finding can be applied to paroxysmal and persistent AF [6,7]. In clinical practice, measurement of LAD can provide a window into the status of

• gamma secretase inhibitor The pleasure or reward zone of the

  2018-11-15

  

  The “pleasure” or “reward” zone of the hypothalamus [13,23–25] is congruent with the site of the greatest concentration of hypocretinergic neurons [26,27]. It is important to consider that, in addition to the hypocretinergic neurons, other groups of neurons such as the melanin concentrating-hormone

• br Material and methods br Discussion Compared to the last

  2018-11-15

  

  Material and methods Discussion Compared to the last national survey performed in 2008 [6], an apparent increase of 13% was observed in the frequency of sleep complaints after 4 years, corresponding approximately to an incidence of 29 million Brazilian inhabitants. However, due mainly to the d

• Por otro lado hay escasa evidencia emp rica que

  2018-11-15

  

  Por otro lado, hay escasa evidencia empírica que muestre la existencia de externalidades positivas atribuibles transferases la ied en los países receptores. Como señala Rodrik (1992): “la literatura política de hoy está llena de extravagantes afirmaciones acerca de la existencia de derrames positivo

• En el estudios de la

  2018-11-15

  

  En el estudios de la fecha de siembra del frijol tenciopelo como cultivo de cobertera en el rendimiento de maíz () en condiciones de temporal sin riego de axulio, se concluye que el rendimiento va de las 2.9 hasta las 6.1 ton/ha. El rendimiento de 6.1 ton/ha es similar al de los distritos de riego.

• The response variable of the models is

  2018-11-15

  

  The response variable of the models is binary, defined by the occurrence of at least one type of crime analyzed over the syk inhibitor covered by the victimization surveys (victim). It assumes value 1 if the individual i was victimized and 0 otherwise. Given this characteristic of the dependent var

• One way to acquire knowledge of tacit

  2018-11-15

  

  One way to acquire knowledge of tacit nature, which is embodied in the individual, is through the mobility of qualified personnel (Feldman, 1999; Audretsch and Keilbach, 2005). Thus, the learning-by-hiring plays an important role in the technological learning process of a firm and in the extent of t

• This paper investigates the evolution of the Brazil EU bilat

  2018-11-15

  

  This paper investigates the evolution of the Brazil-EU bilateral trade in the period 2002–2012 and identifies trading opportunities resulting from a trade agreement of Brazil with the EU. The paper employs a computable general equilibrium model, using the 8th version of the standard Global Trade Ana

• Aside from the importance of producing plaque and

  2018-11-15

  

  Aside from the importance of producing plaque and tangle pathology in a dish, the findings by Kim, Tanzi, and colleagues also re-emphasize the importance of exploring the genetics underlying AD. Although many FAD mutations in and have been well-characterized over the past 20years, the advent of more

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