• br The biological investigations of furo d

  2018-11-03

  

  The biological investigations of furo[2,3-d]pyrimidine derivatives revealed that substitution of various groups on the scaffold exerts anticancer activity via inhibition of different kinases. Conclusion Introduction The chemistry of quinazoline derivatives has been a point of interest in th

• The Crystal Palace was probably the first exhibition

  2018-11-03

  

  The Crystal Palace was probably the first exhibition hall of functionalism that utilized the technological advancement of SBHA iron and glass for its building materials and light structural frames for its construction. Banham (1974) praised Paxton\'s Crystal Palace for its functional design of regu

• c-Myc tag A number of reasons may be adduced on why building

  2018-11-03

  

  A number of reasons may be adduced on why buildings perform poorly in meeting users\' needs and expectations. The chief among them is the lack of adequate knowledge of users\' changing needs and preferences by architects and other professionals who design, construct and maintain buildings. This is o

• Design critique is a crucial part of the design

  2018-11-02

  

  Design critique is a crucial part of the design process in design studios and is related to tutor-to-student and student-to-student interaction and communication. In terms of the kinds of dialog that transpire among people in the critique process, architectural design studios (ADS) have developed th

• br Discussion Based on a literature review it

  2018-11-02

  

  Discussion Based on a literature review, it is stated that there are two requirements for tension pneumocephalus to develop after a VP shunt: the presence of a CSF diversion system causing a decrease in intracranial pressure and the existence of a craniodural defect. In the presence of a craniodu

• br Traumatic thoracolumbar spine fractures

  2018-11-02

  

  Traumatic thoracolumbar spine fractures Traumatic fractures of the thoracolumbar spine, particularly the thoracolumbar junction (T10–L2), are the most common fractures of the spinal column. Percutaneous pedicle screw instrumentation (PPSI) has been used for treating various trauma patterns. For

• Introduction br Definition of MDTs An MDT is

  2018-11-02

  

  Introduction Definition of MDTs An MDT is defined as “a group of people of different healthcare disciplines, which meets together at a given time (whether physically in one place, or by video or teleconferencing) to discuss a given patient and who are each able to contribute independently to the

• One of the most prominent and serious side effects

  2018-11-02

  

  One of the most prominent and serious side effects of NSAIDs is occurrence of gastrointestinal damage (ulcerogenicity). Hence, it was necessary to test our compounds for their ulcerogenicity potential. In the present study, subacute treatment of TAPP (8mg/kg, p.o.) did not cause severe ulcerogenicit

• caspofungin The impact of seaweed chocolate used as

  2018-11-02

  

  The impact of seaweed chocolate used as a nutritional supplement on the blood parameters is presented below in Table 7 and Fig. 1. Table 7 indicates the effect of seaweed chocolate on caspofungin levels of the selected girls after a period of 120 days. The result of the study reveals that the mean

• SAR 405 br Conclusions Our findings show that the early

  2018-11-02

  

  Conclusions Our findings show that the early differentiation state and the multipotent character of unrestricted somatic stem SAR 405 from umbilical cord blood is reflected by specific epigenetic signatures of key pluripotency-regulating genes. The stem cell genes OCT4, NANOG, SOX2, and hTERT ar

• KRAB associated protein KAP also known as

  2018-11-02

  

  KRAB-associated protein 1 (KAP1, also known as TRIM28 and TIF1β) is a novel Oct3/4-dependent transcription factor that regulates pluripotency (Seki et al., 2010). KAP1 was initially identified as an interaction partner of KRAB-domain containing zinc finger transcription factors (Friedman et al., 199

• In our reprogramming culture aside from

  2018-11-02

  

  In our reprogramming culture, aside from insulin production, we also observed expression of α and δ cell hormones, glucagon and somatostatin, respectively in a sub-population of cells. This is likely due to the constitutive expression of reprogramming factors Ngn3 and Pax6. Both transcription factor

• br Introduction Meiosis is the key step of gametogenesis

  2018-11-02

  

  Introduction Meiosis is the key step of gametogenesis, which ensures the production of haploid gametes from their diploid precursors and the recombination of genetic materials from the parents. For lower eukaryotes such as yeasts, meiosis is initiated under unfavorable environmental conditions wh

• hiv protease inhibitors Films of nm thickness were deposited

  2018-11-02

  

  Films of 200–600nm thickness were deposited in vacuum (10Torr) onto various substrates:glass with indium-tin oxide (ITO) coating (conducting amorphous); The temperature values of the evaporator and the substrate were selected in view of our goal of facilitating the self-assembly processes during fi

• One possible reason why lasing characteristics deteriorate a

  2018-11-02

  

  One possible reason why lasing characteristics deteriorate at high injection levels in materials with a low band gap may be non-radiative Auger recombination, which can have a resonant character under certain conditions, leading to a marked increase in the recombination rate [3]. Studying the recomb

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