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Ranolazine During ischemia the impact of CK
2019-10-02
During ischemia, the impact of CK2 on mitochondria varies in different organs/tissues. For example, CK2α upregulation during ischemia leads to disrupted mitochondrial homeostasis and mediates cardiomyocyte ischemic injury [31]. Specifically, ischemia/reperfusion (I/R) progressively increases CK2α to
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Introduction Postoperative delirium POD is a potentially deb
2019-10-02
Introduction Postoperative delirium (POD) is a potentially debilitating disorder experienced by many elderly patients admitted to a surgical intensive care unit (ICU) after noncardiac surgery. Delirium is often defined as acute cognitive dysfunction that is characterized by an altered mental status
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br Acknowledgments We are thankful to the University of
2019-10-02
Acknowledgments We are thankful to the University of Guilan Research Council for partial support of this work. Introduction It is significant to predict the mass, number and velocity distribution of BAD generated by RHA subjected to penetration of EFP by the thickness of target and the impact
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In this study we also conducted an analysis comparing the
2019-10-02
In this study, we also conducted an analysis comparing the expression profiling of Hh genes among the sarcomas investigated. In these tumors, the IHH gene showed a higher expression level than PTCH1 gene in RMS and SS samples (pSpautin-1 in human RMS cell lines as well as mouse NIH-3T3 fibroblasts.
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Despite many studies having demonstrated the importance of
2019-10-02
Despite many studies having demonstrated the importance of connexin43 (Cx43), the most abundant connexin in bone cells, for bone development and turnover during the last decade [27], little is currently known about GJIC and Cx43 in primary bone tumors. In this report, we analyzed the specific role o
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br Physiological roles for EPAC isoforms
2019-10-02
Physiological roles for EPAC isoforms: vascular function The effects of cAMP on limiting vascular endothelial cell (VEC) inflammation and vascular smooth muscle cell (VSMC) proliferation have been well documented 36, 37, 38. However, recent work has demonstrated that several key effects of cAMP i
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Enhanced responses to varying concentrations of bronchoconst
2019-10-02
Enhanced responses to varying concentrations of bronchoconstrictors, such as MCh, and airway obstruction are characteristic of Bacitracin and common to other clinical states, including chronic obstructive pulmonary disease, lung transplantation, and infection- or chemical agent-induced airway inflam
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br Roles of DDR in
2019-10-02
Roles of DDR1 in epithelial cell differentiation Roles of DDR1 in cell migration, and invasion Dichotomous functions of DDR1 in disease progression Conclusions and perspectives The switch in SC 560 and from DDR1 to DDR2 during EMT is another important issue. The DDRs may exert distinct o
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Introduction Myclobutanil MCL RS chlorophenyl H triazol
2019-10-01
Introduction Myclobutanil (MCL), (RS)-2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile (Fig. 1), is a broad-spectrum systemic triazole fungicide with protective, eradicative, and curative action (University of Hertfordshire, 2018). It is employed to control pests such as powdery mild
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EBI and its ligand s EBI was found
2019-10-01
EBI2 and its ligand(s) EBI2 was found in a screen of upregulated genes in human B cells upon infection with EBV [1]. EBI2 is a G-protein (Gαi type) coupled receptor [2] but as long as 18 years after its discovery the nature of its ligand remained undisclosed. With the help of transfected cell lines
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Studies also provide evidence that cytokines such
2019-10-01
Studies also provide evidence that cytokines such as TGF-β, a TH3-type cytokine, may also play a role in airway remodeling. Data obtained by Cohen et al suggest that TGF-β1 can induce human BSMC proliferation by increasing the expression of IGFBP-3. Hence, the mitogenic action of TGF-β1 could be rel
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The following are the supplementary data related to this
2019-10-01
The following are the supplementary data related to this article. Acknowledgments Introduction Drug-resistant epilepsy (DRE) occurs in approximate 30% of patients who suffer from epilepsy [1]. Temporal lobe epilepsy (TLE) is one of the most common partial seizures and the common cause of DRE
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DHT Although differences in several nociceptive tests
2019-10-01
Although, differences in several nociceptive tests have previously been described across strains (Mogil et al., 1999), it is the first time that pain sensitivity in response to chemical and thermal stimuli has been evaluated in B6,129CRHtklee mice. Our results showed no differences in pain sensitivi
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Hyper Assembly To evaluate the new quadrupolar CPA qCPA the
2019-10-01
To evaluate the new quadrupolar CPA (qCPA) the pure fluid properties of CO2 are predicted both in the critical region and in the compressed liquid region. The model is furthermore applied for the prediction and correlation of binary mixtures with CO2 and n-alkanes, water, alcohols and a few quadrupo
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The rate of protein degradation is often affected
2019-10-01
The rate of protein degradation is often affected by N-starvation [12], therefore, we examined the influence of N-starvation against the appearance of CEPs. N-starved cucumber cotyledons contained less amounts of protein and Rubisco, but the temporal changes in protein and Rubisco contents were simi
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