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br Introduction Radiotherapy is the most common modality for
2018-10-25
Introduction Radiotherapy is the most common modality for treating human cancers. About 80% of the patients need such treatment either for curative or palliative purpose [1]. Radiation exposure may produce many harmful effects on living organisms [2]. Gamma irradiation initiates chemical changes
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The rest of the paper will be organized
2018-10-25
The rest of the paper will be organized as follows: Section 2 will be theoretical background and literature review, Section 3 will be conceptual model and hypothesis, Section 4 will be on research methodology, Section 5 will be research results, Section 6 will be discussion of the findings and Secti
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Our data strongly and logically suggest a
2018-10-24
Our data strongly and logically suggest a decreased self-renewal potential in Ptp4a3-KO tumor-initiating Spadin and, in consequence, an inability to form secondary tumors in vivo. The process of tumorigenesis after carcinogen treatment is exceedingly complex and undoubtedly includes the role of str
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Actin dynamics are crucial for Hippo
2018-10-24
Actin dynamics are crucial for Hippo signal transduction, as evidenced by the fact that inhibiting 3-Methyladenine manufacturer cytoskeleton dynamics initiated Hippo signaling in both Drosophila and mammalian cells (Dupont et al., 2011; Fernandez et al., 2011). Both actin polymerization inhibitor L
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br Materials and methods br Data analysis
2018-10-24
Materials and methods Data analysis All results are presented as means±SEM. Comparisons between groups were analyzed using t-tests (two-sided). Differences with p values of less than 0.05 were considered significant. The p values were corrected for multiple testing procedures and to control ty
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The following are the supplementary
2018-10-24
The following are the supplementary data related to this article. Acknowledgments This study was supported by the Korea Healthcare Technology R&D Project, Ministry of Health, Welfare, and Family Affairs, Republic of Korea (Grant no. A120262) and a 2012 grant (10172KFDA993) from the Korea Food &
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br DNA fingerprinting analysis The target
2018-10-24
DNA fingerprinting analysis The target regions of genomic DNA were amplified by Polymerase chain reaction (PCR). The PCR was carried out using a Thermocycler type PTC100 (MJ Research Inc) for 35cycles and each cycle contained 96°C for 30s, 56°C for 30s and 72°C for 30s. The following primer seque
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AVE 0991 Endurance exercise training results in adipose lipo
2018-10-24
Endurance exercise training results in adipose lipolysis and attenuation of fibrosis (Kawanishi et al., 2013a) and inflammation (Linden et al., 2014; Vieira et al., 2009) in adipose and skeletal muscle, independent of weight loss. Thus, participation in an endurance training program is a well-establ
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Main Text These are exciting times for stem
2018-10-24
Main Text These are exciting times for stem cell research and its application to human health. Unprecedented opportunities now exist to harness the power of stem amantadine hcl to understand and treat disease. We continue to learn more about the potential of stem cells of many different types to co
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br Introduction Mammary gland development is controlled
2018-10-24
Introduction Mammary gland development is controlled by the endocrine system, in particular by the ovarian steroid hormones, estrogen and progesterone, and by the pituitary hormones, growth hormone (GH) and prolactin. Studies in animal models showed that GH deficiency impairs mammary gland develo
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In their letter Sadek et
2018-10-24
In their letter, Sadek et al. refer to other studies showing robust and reproducible regeneration. However, none of the studies published to date (Haubner et al., 2012; Heallen et al., 2013; Jesty et al., 2012; Naqvi et al., 2014; Strungs et al., 2013) actually performed apex resection on postnatal
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To address this need we have developed
2018-10-24
To address this need, we have developed a functional imaging approach for CSC identification. The stem cell phenotype in embryonic stem proteases (ESCs) is maintained by a central triad of master transcriptional regulators, OCT4, SOX2, and NANOG, which promote stemness by upregulating genes involve
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br Introduction Advances in stem cell based therapies
2018-10-24
Introduction Advances in stem-cell-based therapies may help overcome CNS disorders such as spinal cord injury (SCI). Transplantation of neural stem/progenitor pppa (NS/PCs) has yielded beneficial effects and improved functional recovery in SCI animal models (Cummings et al., 2005; Hofstetter et
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These fate analyses relied on the
2018-10-24
These fate analyses relied on the restriction of Krox20 expression to BC hydroxylase inhibitor during early PNS development. However, from embryonic day 15.5 (E15.5), Krox20 also is expressed in Schwann cells (Topilko et al., 1994), thereby preventing later analysis of BC derivatives. To circumvent
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Our limited understanding of huSC biology can be attributed
2018-10-24
Our limited understanding of huSC biology can be attributed in part to the difficulty of obtaining tissue samples and of isolating a pure population of huSCs (Boldrin et al., 2010). By comparison, techniques for the prospective isolation of mouse SCs have identified a well-defined myogenic SC popula
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